If you’re considering trying derma rolling to help improve your skin’s texture and appearance, you may be wondering if you need to use a special serum too. Is layering on a serum afterward really necessary to get good results? Or can you effectively rejuvenate your skin with needling alone?
According to our experience at Face Med Store, using a serum in your derma rolling routine can provide additional nourishment, hydration, and skin-enhancing benefits. However, serums are not absolutely required in order to see results from derma rolling alone.
Can You Use a Derma Roller Without Using Serum?
Yes, you can perform dermarolling without applying a serum afterward and still experience collagen stimulation and skin rejuvenation.
According to a study conducted by the National Center for Biotechnology Information (NCBI), histological examination of skin treated with four microneedling sessions one month apart showed up to a 400% increase in collagen and elastin deposition at six months postoperatively.
The minor injuries caused by the microscopic needles trigger your skin's natural wound-healing response. This boosts the production of collagen and elastin to plump, firm, and smooth the complexion.
However, while serums are not essential, they can provide added skin benefits when paired with microneedling.
A study titled "Derma rollers in therapy: the transition from cosmetics to transdermal drug delivery" found that derma rollers create micropores in the skin, which can be utilized to either induce collagen production or permeate applied formulations to the site of action within the skin. The serum nutrients can better penetrate into the micro-punctures created by the roller for enhanced absorption and effectiveness.
Is Serum Necessary for Derma Rolling?
While you can derma roll without serum, applying a topical serum after your microneedling session is recommended to amplify the anti-aging and rejuvenating effects on your skin.
According to a study published in PLOS ONE, microneedling plays a role in dermal remodeling, increases epidermal differentiation, and might also have a direct effect on collagen synthesis.
The tiny channels created by the microscopic needles allow vital ingredients like hyaluronic acid, vitamin C, peptides, and growth factors to be transported below the skin's surface where they can improve texture, increase hydration, and stimulate healthy collagen.
What Serum Should I Use with a Microneedle Roller?
With so many facial serums on the market, choosing the right one to complement your at-home microneedling can seem tricky. Face Med Store suggests looking for serums that contain one or more of these skin-enhancing ingredients:
Hyaluronic acid
Attracts and binds moisture to the skin for hydration. A 2021 study evaluated a hyaluronic acid serum for facial photoaging. Participants applied the serum to one side of their face for 6 weeks. Corneometry showed that the serum increased hydration by 55% versus untreated skin.
Participants and evaluators also observed improvements in plumpness, smoothness, and overall appearance. The researchers concluded hyaluronic acid serum significantly hydrates and improves photoaged skin across Fitzpatrick skin types.
Glycerin
Another humectant that draws water into the skin. A 2017 study found daily application of a fluid with hyaluronic acid, glycerin, and Centella asiatica extract improved skin hydration for 24 hours and enhanced barrier function.
Aloe vera
Soothes, calms, and moisturizes skin while providing wound healing benefits. A systematic review found Aloe vera can prevent skin ulcers and treat wounds. It concluded Aloe vera retains skin moisture and integrity and prevents ulcers.
Vitamin C
A powerful antioxidant that stimulates collagen production and helps even out skin tone. A study conducted in 2023 found that microneedling with topical vitamin C and E serum showed better results in treating recalcitrant facial melasma compared to microneedling alone.
Vitamin B5
This hydrating vitamin conditions and softens skin while also strengthening the skin barrier, which is disrupted during microneedling. It provides restoration and moisture essential for skin healing after derma rolling, as proven by a 2014 study.
Peptides
Amino acid chains that signal the skin to increase collagen production for firmer, more youthful-looking skin. A PLoS ONE study found that microneedles can substantially enhance the skin penetration of peptides.
What's the Best Serum to Use with a Derma Roller?
There is no universal “best” serum for derma rolling that suits all skin types and concerns. According to our experience, the ideal serum depends on your individual skin goals:
| Skin Goal | Recommended Serum Ingredients | Benefits |
|---|---|---|
| Anti-Aging | Vitamin C, vitamin B5, peptides, growth factors | Minimize lines, boost collagen density, restore firmness |
| Acne Scars | Niacinamide, centella asiatica, peptides | Fade marks |
| Dryness | Hyaluronic acid, glycerin, aloe vera | Attract and seal |
Always patch-test any new serum on your forearm before applying it after microneedling. Ensure it does not cause any irritation or reaction before using it on your face.




