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The Hamilton-Norwood scale (sometimes only referred to as "Norwood scale") is the primary classification system used in the medical field to gauge the degree of male pattern baldness. This measurement scale was first introduced by James Hamilton in the 1950s and later revised and updated by O'Tar Norwood in the 1970s.

Men tend to lose their hair in a few common patterns over the development of many decades. The Hamilton-Norwood scale provides quick reference images that show distinct stages of balding. This is important for doctors to classify the stage of balding.

There are many other classification scales used by doctors, researchers, and hair transplant surgeons. Different classification scales include male and female, or only female, but Hamilton-Norwood is typically used by practitioners when discussing male pattern baldness.

It presents a reference point to diagnose the degree of baldness, consider treatment options, and measure the effectiveness of any treatment.

The Seven Stages of Hamilton-Norwood

The Hamilton-Norwood scale has seven steps. Each step marks the severity and pattern of hair loss.

Stage 1. There is a lack of bilateral recessions along the anterior border of the hairline in the frontoparietal regions. No notable hair loss or recession of the hairline.

Stage 2. There is a small recession of the hairline around the temples. Hair is also lost, or sparse, along the midfrontal border of the scalp, but the depth of the affected area is much less than in the frontoparietal regions. This is commonly referred to as an adult or mature hairline.

Stage 3. The first signs of significant balding appear. There is a deep, symmetrical recession at the temples that are only sparsely covered by hair.

Stage 3 vertex. The hairline stays at stage 2, although there is notable hair loss on the crown of the scalp (the vertex).

Stage 4. The hairline recession is harsher than in stage 2, and there is scattered hair or no hair on the vertex. There are deep frontotemporal recessions, usually symmetrical, and are either bare or very sparsely covered by hair.

Stage 5. The areas of hair loss are more significant than in stage 4. They are still divided, but the band of hair between them is thinner and sparser.

Stage 6. The connection of hair that crosses the crown is gone with only sparse hair remaining. The frontotemporal and vertex regions are joined together, and the extent of hair loss is more significant.

Stage 7. The most drastic stage of hair loss, only a band of hair, going around the sides of the head persists. This hair usually is not thick and might be dainty.

Norwood class A. This is a somewhat different and less common classification of hair loss. Norwood also defined a Type A variant from his standard classification system, which is distinguished by two major features and two minor features.

Major features

1) the border of the hairline grows to the rear without leaving an island of hair in the mid-frontal region

2) there is no synchronous development of a bald area on the vertex. Rather, the frontal hairline recession keeps progressing to the rear of the scalp.

Minor features

1) there is sparse hair scattering in the area of hair loss  

2) the horseshoe-shaped areas of hair that continue on the side and back of the scalp tend to be more extensive and touch higher on the head.

How is male pattern baldness diagnosed?

Common male pattern baldness is usually diagnosed based on the form and pattern of hair loss, along with a comprehensive medical history, including questions about the predominance of hair loss in your family.

How is hair loss treated?

Hair loss treatments are most potent when started early. It's more manageable to slow down hair loss than it is to incite new hair growth. Hair follicles that stop creating hair become dormant after about two years and can't be reactivated. However, there are ways to rejuvenate your hair follicles and start-up hair growth, such as Laser Hair Growth Helmets, and Pep Factor.

Laser Hair Growth Helmets. Low-level laser therapy is known as red light therapy and cold laser therapy, highlights, and empowers photons in the scalp tissues. These photons get absorbed by weak cells, which then encourages hair growth. At FACE, we use this type of treatment in our Laser Hair Growth Helmets.

Pep Factor. This serum is designed from the first drop with the intention of magnifying Fibroblast. Fibroblast Growth Factors (FGF) directs a range of various biological functions, including cellular proliferation, durability migration. FGF is also responsible for the renewal of tissue, including skin and hair follicles. UMA's research laboratory has designed this unique formula. 

Androgenetic alopecia (male or female patterned baldness) is a prevalent form of hair loss in both men and women. Hair is lost in a clear pattern, starting above both temples. As time passes, the hairline shrinks to form an infamous "M" shape. Hair also thins at the top, often advancing to partial or total baldness.

The pattern of hair loss found in women is different from male-pattern baldness. For women, the hair becomes thinner all over the head, and the hairline does not shrink. Androgenetic alopecia in women seldom leads to total baldness.

How Common Is Androgenetic Alopecia?

Androgenetic alopecia is a widespread cause of hair loss in both men and women. This kind of hair loss afflicts approximately 50 million men and 30 million women in the United States. Androgenetic alopecia can start as quick as a person's teens and the risk rises with age; more than 50 percent of men beyond the age of 50 have some stage of hair loss. In women, hair loss is most apparent after menopause.

What Causes Androgenetic Alopecia?

A variety of hereditary and environmental circumstances represent a part in inducing androgenetic alopecia. Although researchers are examining risk factors that may add to this condition, most of these factors remain hidden. Researchers have discovered that this kind of hair loss is linked to hormones called androgens, especially an androgen called dihydrotestosterone. Androgens are essential for normal male sexual maturation before birth and during puberty. Androgens also have other vital roles in both males and females, such as managing hair growth and sex drive.

Hair growth starts beneath the skin in structures called follicles. Each strand of hair grows typically for 2 to 6 years, goes into a resting phase for some months, and then falls out. The sequence starts over when the follicle begins growing a new hair. A spike in the levels of androgens in hair follicles can cause a shorter cycle of hair growth and produce shorter, more delicate strands of hair. Unfortunately, this also creates a delay in the growth of new hair to replace strands that are shed.

Two Ways Reverse Androgenetic Alopecia

Laser Hair Growth Helmets. Low-level laser therapy is known as red light therapy and cold laser therapy, highlights, and empowers photons in the scalp tissues. These photons get absorbed by weak cells, which then encourages hair growth. At FACE, we use this type of treatment in our Laser Hair Growth Helmets.

Laser helmets are indispensable in treating hair loss, but not all lasers are produced equal. FACE's product has 272 diode lasers that are developed especially for high-efficiency lasers that allow releasing the most significant volume of light and coverage for the total scalp area. The lasers are precisely crafted to encourage supreme hair growth. Laser Helmet lasers are known to reverse the thinning of follicles. Follicles will then ultimately return to their healthy natural state after being exposed to our specific lasers. 

Pep Factor. This serum is designed from the first drop with the intention of magnifying Fibroblast. Fibroblast Growth Factors (FGF) directs a range of various biological functions, including cellular proliferation, durability migration. FGF is also responsible for the renewal of tissue, including skin and hair follicles. UMA's research laboratory has designed this unique formula. 

Fibroblast growth factor (FGF)2/basic FGF is a member of the fibroblast growth factor family. Its role in skin tissue healing is well known in the medical community. Still, the function of other FGFs in skin tissues remains unclear. In this recent study, they studied FGF composition patterns in the heart, liver, skin, and kidney tissues. Compared to other tissues, only four FGFs were dominant in the skin.

To discover FGF function in the tissue healing cycle, mice fibroblast cells were treated with FGF2, FGF10, and FGF21, and cell migration was closely watched. The results showed that FGF treatment improved cell migration, which is an essential step in wound healing. Also, FGF therapy improved the activity of c-Jun N-terminal kinase (JNK), which is a crucial regulator of fibroblast cell movement. 

How Does It Heal Wounds?

Human genomes contain 23 members of the fibroblast growth factor family, which are necessary for metabolism and growth. FGF21 is the most researched family member and has been most commonly found in the liver early in development. Skin tissue repair needs the assistance of different cell types, including keratinocytes, fibroblasts, endothelial cells, macrophages, and platelets. 

Fibroblast cell generation and migration, collagen deposition, and remodeling wound contraction, and angiogenesis are essential steps of tissue repair. Extracellular matrix forms the most significant component of the dermal skin layer; therefore, the repair of ECM is critical to wound healing. Fibroblasts form an essential cell layer that aids in the production and restoration of the ECM, and their proliferation and migration is vital for the formation of granulation tissue and skin repair. 

Is FGF Effective at Healing the Skin?

GF2/bFGF is a member of the FGF family, and its effectiveness in the growth of fibroblast cell migration is recognized in the medical community. In the study, it was observed that FGF2, FGF7, 10, and 21 are highly expressed in skin tissue. Previously, the role of FGF21 in glucose homeostasis has been well known, and its generation is started by stress in the liver and heart. However, in the study, FGF21 appearance was shown to be most significant in the skin, where expression was even higher than in the liver.

Even more impressive is that FGF21 was shown to accelerate the migration of mouse fibroblast cells, similar to FGF2. Also, FGF10 was identified as predominant in the skin and even accelerated cell migration. FGF2 has been known to expedite fibroblast cell migration via activation of the phosphoinositide 3-kinase-Ras-related C3 botulinum toxin substrate 1-JNK signaling pathway. Something else discovered in the study was that FGF2, 10, and 21 treatment increased JNK phosphorylation levels. FGF7 has the highest expression of all FGFs in the skin; however, overexpression of FGF7 in fibroblast cells did not alter cell migration speed, implying that FGF7 may have alternative roles in skin tissue.

Numerous FGFs were comparatively highly expressed in the heart, liver, and kidney, implying the potential roles of these FGFs in different tissues. Notably, FGF1 was one of the dominant FGFs in all the tissues tested besides the skin. The findings of the study show that FGF family members FGF2, 10, and 21 coordinate to stimulate the FGF signaling pathway, which is essential in the development of wound repair. 

Pep Factor for SKIN Rejuvenation is one of Face's most advanced serums. Pep Factor can promote healthy skin repair and give your skin a more youthful appearance. As you can tell by this post, this product is excellent for multiple kinds of uses due to its basic Fibroblast Growth Factors. 

FGF(Fibroblast Growth Factors) incites hair growth and are involved in the management of hair morphogenesis and the hair growth cycle. A recent study investigated the hair growth-promoting liveliness of three approved growth factor drugs, fibroblast growth factor 10 (FGF-10), acidic fibroblast growth factor (FGF-1), and basic fibroblast growth factor (FGF-2), and the method of how they all acted. 

A Rise In Hair Loss

Hair is deemed an accessory structure of the integument along with oil glands, sweat glands, and nails. Hair follicle formation needs the intricately managed regulation of apoptosis, proliferation, and differentiation. Hair follicles are mini-organs that, during postnatal life, cycle through periods of anagen (growth phase), catagen (regression phase), and telogen (resting phase)

Hair loss is regularly not a life-threatening event; however, it can severely impact one's life. The number of patients suffering from hair loss has risen in the past few years. Some of these individuals deal with a hit to their self-esteem, confidence, and vitality.  

Does FGF Stimulate Hair Growth?

Fibroblast growth factors have potential application in hair growth. The study that this article is based on tested their results on rats. 

To assess the hair growth potential of FGFs, they topically applied FGF-1, FGF-2, and FGF-10 on shaved mice. Each week they would determine the amount of hair growth based on the color of the skin.

At two weeks, three FGFs produced black coloration in the shaved skin of the mice. FGF-10 group expressed the most black coloration, while very less visible hair growth and black coloration were observed in the control group. 

At three weeks, the FGFs group showed increased hair growth, and FGF-10 stimulated hair growth over 50% of the shaved area. 

At four weeks, they observed that hair growth from FGF-1 and FGF-2 was only happening in select areas. However, the control group showed less hair growth. 

To confirm that FGFs promoted hair growth, they measured the length of 10 hairs plucked from each mouse at 2, 3, and 4 weeks. The length and strength of hairs in FGF-10, FGF-1, and FGF-2 treated group was remarkably longer than that of the control group, and FGF-10 had the most vigorous activity of hair growth. 

Pepfactor is created from the start with the purpose of magnifying Fibroblast. FGF directs a range of multiple biological functions, including cellular proliferation, durability migration. FGF is also responsible for the regeneration of tissue, including skin and hair follicles. Facemed's Pep factor utilizes every facet of FGF to ensure optimal results. 

Results

FGF increased the number and the size of hair follicles during anagen phase induction. An improvement in the number of hair follicles is an indicator for the transition of hair growth from the telogen to anagen phases. The hair in FGF-10, FGF-1, and FGF-2 treated group appeared much more soon than those in the control group. While the number of hair follicles of the relative area in FGFs managed group was greater than in the control group, topical application of FGF-10 showed the maximum amount of hair follicles as compared to FGF-1 and FGF-2 groups.

Platelet-rich plasma (PRP) is created by combining platelets found in whole blood. It can aid in tissue regeneration, bone regeneration, and wound repair.

Platelet-rich plasma treatment has also been suggested to promote hair growth, encourage cell survival and reproduction, and lengthen the anagen phase of the hair cycle.

During the treatment, a technician draws your blood and spins it in a centrifuge to separate the platelets and plasma. Doctors then inject the plasma, which helps repair blood vessels, promote cell growth and wound healing, and stimulate collagen production.

PRP kits

Selphyl. This product allows for the prolonged release of platelet growth factors in the scalp to help hair grow. This extended-release stimulates stem cells, prolongs dermal papillae cell survival, and increases angiogenesis. These factors combine to lengthen the anlagen phase of hair growth and shorten the catagen (resting) phase. The result is increased hair diameter and hair follicle durability.

ReGen. The product's main ingredient, Minoxidil, was developed in the 1950s to treat conditions, such as ulcers and high blood pressure. Researchers discovered that the product could revive hair follicles and reverse both male and female pattern baldness (androgenic alopecia). The ingredient is essentially a potassium channel opener capable of causing the hyperpolarization of cell membranes.

Eclipse. Tends to offer fewer steps than other PRP kits available. It is an established system that is based on blood separation according to mass using a unique division gel. The system allows for the preparation of complete Platelet-Rich Plasma (PRP) with optimal platelet groups and cellular content.

Magellan. It cost much more than the other systems, but the results will typically be more prominent. The method begins by drawing blood, 60-120cc. The blood is then put in the Magellan processor to insulate the PRP, which takes about 15 minutes per 60cc of blood. During this time, the scalp is dulled up with both topical creams as well as shots. When numb, the scalp is injected with a vitamin mixture as well as with the solution. Afterward, the PRP injection is then performed. 

FGF Kits

Pepfactor is created from the start with the purpose of magnifying Fibroblast. FGF directs a range of multiple biological functions, including cellular proliferation, durability migration. FGF is also responsible for the regeneration of tissue, including skin and hair follicles. UMA's research laboratory has designed this unique formula. 

How Does FGF Compare?

Scientists identified the Fibroblast Growth Factor (FGF) in pituitary extracts in 1973. FGFs are cell proteins that exert their physiological functions through coordinating developmental pathways, managing events in the early embryo through the growth of multiple organ systems. A defining feature of FGFs is that they adhere to heparin and heparan sulfate. 

In this research study, scientists compiled an abundance of data to establish the strengths of FGF for the use of hair regrowth. Here are some of the results seen in the study.

The data and examination of FGF on hair growth are reliable, and I encourage you to read the full report to see how comprehensive the research was. I believe this evidence shows that FGF is an excellent alternative to using PRP for hair growth. 

You don't have to accept it anymore that your hair and skin are aging. The science is here to slow down aging and even bring back youthful-looking skin drastically. Fibroblast Growth Factor is revolutionizing how we treat our aging skin and hair.

Fibroblast Vs. FGF

Scientists discovered Fibroblast Growth Factor (FGF) in pituitary extracts in 1973. FGFs exert their physiological roles through regulating developmental pathways, controlling events in the early embryo through the development of multiple organ systems. A defining property of FGFs is that they bind to heparin and heparan sulfate.

Fibroblast are cells that are involved in crucial elements for healthy skin and hair development. These cells generally act as circulating molecules that activate surface receptors. Put simply, they rejuvenate the skin and hair to promote new growth.

Utilizing the fibroblast growth factor will give your skin new life and grant thickness and even growth to your hair. How can you start using FGF? 

We at FACE have a groundbreaking product that can support you in maintaining youthful skin and hair. 

Pep Factor is designed from the ground up to enhance Fibroblast cells. FGF regulates a range of various biological functions, including cellular proliferation, survival migration, differentiation as well as the regeneration of tissue, including skin and hair follicles. UMA's research laboratory has created this unique formula. 

How does it work?

Effects On Skin

Skin is the largest organ of the human body, protecting it against external aggressions, such as microorganisms, chemicals, and physical agents, including sun rays. Aging is a complex and constant biological process characterized by cellular and molecular changes, with progressive reduction of the body's capacity to keep homeostasis and an increase in senescence and apoptosis. This process varies between individuals and from organ to organ, and skin exhibits the effects of the passage of time most evidently.  

Also, the use of ultraviolet radiation, excessive alcohol consumption, tobacco abuse, environmental pollution, and other factors can influence and accelerate this physiological process, causing premature skin aging.

Healing the Skin

By stimulating the proliferation of cells such as fibroblasts, growth factors play a significant role in the skin repair process, inducing reepithelialization through the replacement of disorganized collagen and elastin structures and the reposition of the extracellular matrix in aged skin.

The use of growth factors is a new anti-aging strategy to rejuvenate and reverse the signs of photoaged skin. Understanding the role of growth factors in wound healing may predict their role in skin infrastructure remodeling and skin rejuvenation.

Hair Growth

In this study, the researches compiled plenty of evidence to support the powers of FGF for the use of hair regrowth. Here are some of the results observed in the study.

The evidence and testing of FGF on hair growth are substantial, and I invite you to read that full report to see how extensive the research was.  

In Conclusion

Evidence shows that FGF works, and at FACE, we have the products necessary for you to use on your hair and skin. Start rejuvenating your skin to maintain

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