PRP VS. PRF for Hair Loss: Which is the Better Treatment?

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PRP vs PRF treatment for hair loss condition

Platelet-rich plasma and platelet-rich fibrin are some of the most effective non-surgical hair restoration treatments. Both of these injectable solutions contain autologous growth factors that regenerate the hair follicles and provide them with enough nutrients for hair growth. Because these options are similar to each other, many patients wonder which is the better treatment for their type of hair loss.

So which is the better treatment for hair loss between platelet-rich plasma and platelet-rich fibrin? As PRF is an advanced and refined version of PRP, it’s definitely a more effective treatment, but the better procedure would still depend on the treatment area and your priorities. PRF contains a higher concentration of platelets than PRP as it’s processed at a slower speed. PRF also doesn’t require anticoagulants during synthesis, unlike PRP.


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Comparing PRP VS. PRF 

Platelet-rich plasma and platelet-rich fibrin are both forms of regenerative medicine that have proven their effects in reactivating dormant hair follicles by aiding the production of stem cells and collagen. While they involve pretty similar procedures and use of healing factors, there are still stark differences in terms of processing speed, platelet count, what they consist of, release times, cost, and effectiveness.

1) Processing Speed

Medical professionals prepare platelet-rich plasma and platelet-rich fibrin by gathering your blood sample and processing them in a centrifuge. The machine spins normal blood to separate blood components and gather the needed growth factors for the procedure as the heavier cells in the blood sink and the lighter ones, like plasma and platelets, float. Practitioners will then extract concentrations of platelets.

But with harvesting platelet-rich fibrin as a hair loss treatment, the centrifuge’s spin speed would be lower. Processing the blood sample at a slower speed will still retain stem cells, fibrin, and some white blood cells. Because of this, what you have is a serum with higher concentrations of growth factors because it contains platelets, stem cells, and fibrin. The speed of centrifugation also kept the individual cells intact.

2) Platelet Count

Platelet-rich fibrin has a higher platelet concentration than platelet-rich plasma. The speed of centrifugation when harvesting PRP actually leaves out many platelets from the extracted serum. But the platelet count in this serum is still higher by 3 to 5 times than those found in your blood sample. Platelet-rich fibrin retains more platelets because it’s spun at a slower speed.

3) What They Consist Of

Platelet-rich plasma consists of plasma, which is the liquid portion of the blood that acts as its medium – it’s made of proteins. This plasma is concentrated with platelets, the blood cells that are responsible for wound and tissue healing.

Unlike PRP which only contains plasma and platelets, platelet-rich fibrin also contains white blood cells and fibrin. These blood cells are also beneficial for tissue regeneration, making your hair regeneration procedure more effective.

4) Release Times

Another stark difference between platelet-rich plasma and platelet-rich fibrin for hair regrowth is the release times – PRP releases its concentration of growth factors and platelets after a lot faster than PRF after injection.

This is because processing PRP involves adding anticoagulating factors to prevent blood clotting. In producing PRF, experts allow clotting due to fibrin. The consistency of PRF injections has a matrix or scaffold because of this, which is why the release of growth factors is slower.

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5) Cost

Because of the advanced effects of platelet-rich fibrin, patients can expect it to be more expensive than platelet-rich plasma. The average cost of PRP is around $1000 to $3500 for the initial treatments, with each injection costing around $400. Platelet-rich fibrin costs around $1000 to $5000.

These prices will vary depending on your location and the clinic where you’ll undergo these treatments.

6) Effectiveness

Both procedures are pretty effective in treating male and female pattern hair loss and other types. They also grow thicker hair due to healthy hair shafts, giving you a better hair volume. These treatments are advised to take on the early stages of hair loss. However, there is still a better formula in terms of effectiveness between PRP and PRF.

Because PRF is the more advanced and fine-tuned version of PRP, it’s more effective. PRF is more potent and also contains stem cells, unlike PRP. PRF also has 10 times more growth factors than PRP.

Platelet-Rich PlasmaPlatelet-Rich Fibrin
Processing SpeedQuicker spin speedSlower spin speed
Platelet CountContains fewer platelets than PRF, but has 3 to 5 times more than your blood sampleContains more platelets than PRP
What They Consist OfPlasmaPlateletsFibrinPlateletsWhite blood cellsStem cells
Release TimesQuicker release timeSlower release time
Cost$1000 to $3500$1000 to $5000
EffectivenessStill an effective hair loss treatmentMore effective than PRP

Choose FACE Med Store for PRP and PRF Supplies

PRF and PRP are reliable treatments for hair loss, but because PRF has more advanced technology, it’s more effective. However, the better hair loss treatment will still depend on your degree of hair loss and priorities because PRF is more expensive than PRP.

Ensure the success of both procedures and choose the best partner for medical and beauty supplies. FACE Med Store has been a trusted supplier of medical and cosmetic procedure needs. Visit our website to know more about our offers and promotions.

All content in this blog is for informational purposes only. It is not medical or legal advice. Please consult with lawyer or a medical professional.