PRP Injection vs. Microneedling with PRP for Hair – Which is Better?

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woman receiving prp injection treatment for hair rejuvenation

With all the cosmetic procedures available in the market for hair loss issues, it can really be quite overwhelming to choose the right one for you. With every one of them claiming that they’re an effective alternative for known medications like topical minoxidil, it can really be quite a challenge to decide on which one to go for. This goes for procedures like PRP and microneedling treatment.

So which is better between PRP injection vs. microneedling with PRP for the hair? Simply put, this is a battle between monotherapy and combination therapy, and the simple answer is that combination therapy (microneedling with PRP for hair) is the better option because it combines the benefits of the two for optimal hair regrowth results.


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How Platelet-Rich Plasma Injection Works

Platelet-rich plasma injection is an all-natural autologous plasma, meaning it’s derived from the patient’s own components of blood. It’s done by a blood draw from the patient’s own blood supply. The blood sample will then be processed in a centrifuge to separate the blood cells like white blood cells from platelets, increasing the concentration of platelets in the process.

The patient’s platelet-rich plasma with the concentrated growth factors will then be injected into the affected area of the scalp skin that exhibits hair loss at equal spacing.

These growth factors will help stimulate the growth of a new hair follicle because they’re capable of acting as angiogenic factors, meaning they enable the stimulation of a better blood flow towards the affected area which leads to better oxygen flow and nutrition that the hair needs for hair growth.

How Microneedling Works 

Microneedling is first done by putting numbing cream on the area where the procedure will be done. It uses a handheld device called a derma roller, which has tiny sterilized needles that create micro-injuries to the area of the scalp experiencing hair loss.

These micro-injuries result in the stimulation of collagen production so it’s sometimes referred to as collagen induction therapy, making it a good procedure for hair rejuvenation. For hair growth on the other hand, the micro-injuries may lead to the stimulation of the production of stem cells in the hair follicles, leading to the growth of hair follicles.

Microneedling with PRP: Combining the Benefits And Side Effects of PRP Injection and Microneedling

Microneedling is capable of helping the better absorption of products used for hair loss therapy like platelet-rich plasma. As such, combining the two optimizes the benefits for a variety of conditions linked to hair loss, leading to results that are better than the results of either of the 2 therapies alone.

Similarly, the side effects of both procedures may manifest together as well. These are generally mild, tolerable, and go away on their own so it shouldn’t be a major concern for the patient undergoing the procedure:

MicroneedlingPlatelet-Rich Plasma
mild rednessmild swellingmild bruisingtiny blood formation along the site of treatmentpain at the site of treatment
infection (especially in at-home derma rollers where sterility isn’t ensured)allergic reactions to the numbing creamnerve damage and injury (although this rarely happens and may be attributed to the skills of the healthcare provider performing the procedure)

PEP Factor: An Excellent Formulation for Combination Treatment


It’s been established that combination therapy is generally better than monotherapy in terms of effectiveness as a treatment for hair loss. While PRP is a popular option for combination therapy, another good formulation to consider is PEP Factor, another formulation that can help provide improvements in hair growth.

With its high-quality nourishing ingredients, PEP Factor can help provide optimum hair loss treatment results. It’s safe to be added to other hair restoration treatments because of its topical application and natural ingredients which have minimal side effects when applied. 

PEP Factor’s active ingredients include the basic fibroblast growth factor (bFGF) which can help in the healing process for thicker hair because of its cell growth properties similar to the other growth factors present in the patient’s platelet-rich plasma.

Another active ingredient is the copper peptide, which has antioxidant properties. These antioxidant properties help in lessening hair loss that comes from oxidative stress or the build-up of harmful by-products of oxygen called reactive oxygen species, which may also exacerbate the noticeable hair loss effects of androgenetic alopecia.

PEP Factor, like PRP and microneedling, can also be used in improving skin conditions and skin texture through its ability to help in skin rejuvenation and skin renewal.

Shop at FACE Med Store for the Best Beauty and Medical Supplies

Combining esthetic procedures is the best way to improve the appearance of different types of hair loss like androgenetic alopecia. This is because combining treatments for hair loss results in the building up of the effects of these treatments, causing more optimal and pronounced hair growth effects.

FACE Med Store can help facilitate this combination therapy for hair loss by providing the best medical supplies and formulations for hair regrowth, as well as our highly-trained staff to help guide you in choosing the best products for your hair problems. To know more about the best products for hair care, contact us today at

Learn More: Can Platelet-Rich Plasma Injection Protect Hair From Humidity?

All content in this blog is for informational purposes only. It is not medical or legal advice. Please consult with lawyer or a medical professional.