Want youthful, radiant skin? Korean salmon DNA injections may be the answer, but first, discover if this innovative beauty treatment is right for you.
Korean Salmon DNA injections rejuvenate skin using PDRN, a substance extracted from salmon sperm. This treatment boosts collagen production, improves hydration through hyaluronic acid, and promotes cell turnover.
Studies suggest this process may improve skin elasticity and refine texture, potentially reducing fine lines and enhancing overall appearance. The KFDA has approved this non-invasive procedure. Patients might experience temporary redness or swelling after the injection.
While individual results vary, consistent sunscreen use and a solid skincare routine are crucial for maintaining optimal results.
What Is Korean Salmon DNA Injection?

Salmon DNA injections utilize processed salmon sperm DNA, specifically Polydeoxyribonucleotide (PDRN), to rejuvenate skin.
The processing of PDRN removes potentially harmful proteins, ensuring compatibility with human skin. This purification process highlights PDRN’s regenerative abilities, making it useful for skin repair.
Application of PDRN
These treatments are diverse, covering general skin rejuvenation. They also target specialized areas, focusing on wrinkles and dark circles around the eyes.
Often, PDRN treatments are combined with hyaluronic acid. This combination boosts skin hydration and facilitates repair processes.
Enhancement Formulations
Some formulations include exosomes, further enhancing skin repair and regeneration capabilities. These advanced treatments are sometimes referred to colloquially as “baby skin injection” or “youth vaccine.”
Mechanism of Action
PDRN stimulates collagen production, a key component in skin structure and elasticity. Hyaluronic acid, meanwhile, hydrates the skin, providing immediate plumping effects.
These treatments deliver essential proteins and vitamins, DNA fragments that promote skin cell renewal, and anti-inflammatory compounds.
Addressing Aging
While genetics influence skin aging, DNA-based therapies like PDRN aim to counteract the aging process. They work to heal skin, improve elasticity and firmness, refine texture and tone, address hyperpigmentation, and notably, reduce the appearance of wrinkles.
Regulatory Approval
The Korea Food and Drug Administration has approved these PDRN-based treatments, signifying their safety and efficacy within established guidelines.
How Korean PDRN Injection Works
Polydeoxyribonucleotide (PDRN), sourced from salmon DNA fragments, revitalize skin by stimulating fibroblasts, cells that boost collagen production and overall skin health. This stimulation enhances cellular regeneration and tissue repair.
Increases collagen and elastin production, which improves skin texture. PDRN targets wrinkles, hyperpigmentation, and fine lines. Studies suggest PDRN may improve skin elasticity by approximately 10-20% after several treatments.
Before the procedure, consult with a specialist to assess your skin condition. The skin is then cleansed and sterilized to minimize infection risk. The targeted areas are anesthetized before a PDRN solution is injected via microinjections. Expect to wait 30-60 minutes, based on the size of the treated area.
PDRN’s effectiveness lies in promoting natural skin rejuvenation at a cellular level, leading to subtle, long-lasting improvements, as opposed to acting as a traditional filler. Clinical observations indicate that patients may notice visible improvements within 4-6 weeks of the initial treatment. However, individual results can vary depending on skin type, health, and lifestyle factors.
Advantages of This Treatment
Korean salmon DNA injections offer several key advantages for skin health. They boost skin elasticity and refine texture. Studies show these injections promote collagen production, which is vital for skin structure, leading to improved firmness. Some studies indicate a potential increase in collagen and elastin fibers by up to 20% compared to some traditional treatments, resulting in visibly firmer skin.
The treatment improves skin texture by encouraging the regeneration of healthy skin cells. This process can lessen the appearance of fine lines and encourages a smoother skin tone. Additionally, these injections enhance the skin’s ability to hold moisture, resulting in plumper skin. This increased moisture retention may lead to a more radiant complexion, particularly helpful for individuals with dry skin.
Salmon DNA injections also possess anti-inflammatory properties that can reduce redness and speed up healing. This makes it a possible option for sensitive skin, assisting in the repair of damaged skin. While individual results may vary, research suggests a faster recovery time of up to 15% in treated areas.
Korean Salmon DNA Injection Process

This treatment involves several stages to help you decide if it’s a good fit.
- Consultation Stage:
- First, consult with a professional dermatologist or esthetician.
- They will examine your skin thoroughly.
- They will review your medical history.
- They will explain the treatment process in detail.
- They will answer any questions you have to ensure you are fully informed.
- Pre-Treatment Preparation:
- Before the treatment, stop using any blood thinners, alcohol, and smoking to minimize risks.
- Your skin will be cleaned to ensure a hygienic environment for the procedure.
- Hyaluronic acid may be applied to prepare the skin.
- You might receive local anesthesia to numb the area, reducing any discomfort during treatment.
- Treatment Process:
- During the treatment, the skin is sterilized to prevent infection.
- A topical anesthetic reduces any discomfort you might experience.
- Microinjections deliver the PDRN solution directly into the skin.
- Each session typically lasts between 30 to 60 minutes.
- Depending on your individual case, you may need multiple sessions, which will affect the total cost of the treatment.
- Post-Treatment Care:
- Expect some redness and swelling immediately following the procedure.
- Apply cold compresses to soothe the skin and reduce swelling.
- Use ointments as advised to aid in recovery.
- Avoid strenuous activity, saunas, and hot baths to prevent complications and promote healing.
- Use sunscreen daily to protect your treated skin from sun damage, which is crucial for the healing process and long-term results.
- Maintain a consistent skincare routine to support skin health post-treatment.
- Considerations Before Proceeding:
- Consider the costs involved compared to the potential long-term benefits of the treatment.
- Research the procedure extensively to understand its effectiveness and compare it with alternative treatments.
- This will help you determine if the treatment is the best option for your specific skin concerns and overall health.
Possible Side Effects
Korean salmon DNA injections, while innovative, are associated with several potential side effects that patients should be aware of before proceeding with treatment.
Immediate Reaction Symptoms:
- Local Reaction: Expect redness, swelling, and bruising at the injection site immediately following the procedure.
- Temporary Skin Changes: You may observe temporary, raised lumps similar to small insect bites or needle marks.
- Initial Skin Appearance: The skin might appear red and inflamed right after treatment, with a sensation akin to stinging or irritation.
Allergic Reactions:
- Skin Rashes: An allergic reaction, manifesting as a skin rash, is possible, especially in individuals sensitive or allergic to salmon.
- Interaction with Other Treatments: The injections may interact with certain hyaluronic acid fillers, potentially causing small bumps or, rarely, more serious immune reactions.
Increased Risk Factors:
- Blood Thinners: Individuals on blood thinners have an elevated risk of bruising and bleeding post-injection.
- Contraindications: These injections are not advisable for those with diabetes requiring insulin, those at risk for stroke or heart issues, pregnant women, breastfeeding mothers, individuals with open wounds, or those diagnosed with cancer.
Important Considerations:
- Pre-existing Conditions: Patients should consult with their healthcare provider if they have any pre-existing conditions that might be exacerbated by the injections.
Understanding these side effects and contraindications is crucial for making an informed decision regarding salmon DNA injections. Always seek professional medical advice before undergoing any new cosmetic procedure.
Aftercare Instructions

Following these aftercare instructions promotes optimal healing after a Korean salmon DNA injection.
Skincare:
- Cleanse: Gently cleanse skin with a soap-free cleanser to avoid irritation.
- Moisturize: Apply a lightweight, non-comedogenic moisturizer containing hydrating ingredients like hyaluronic acid to help retain moisture. Studies indicate hyaluronic acid can improve skin hydration by up to 50%.
- Protect: Apply a broad-spectrum SPF 30+ mineral-based sunscreen daily to shield skin from sun damage. Sunscreen reduces the risk of hyperpigmentation.
- Avoid: Refrain from using harsh skincare products or peeling the skin, as this can hinder healing and increase the risk of complications.
Activity:
- Cool: Stay cool and apply cold compresses to treated areas to reduce swelling and discomfort immediately after the procedure.
- Limit: Avoid strenuous exercise, hot environments like saunas, and hot showers for 24-48 hours to minimize sweating and prevent inflammation. Increased blood flow to the face from exercise could potentially worsen swelling during this initial period.
General:
- Protect: Shield skin from direct sun exposure, as UV rays can interfere with the healing process and increase the risk of hyperpigmentation.
- Follow: Adhere to your healthcare provider’s specific instructions for aftercare.
- Avoid: Don’t touch or massage the treated area to prevent infection or dislodging the injected material. Abstain from alcohol, which can thin the blood and potentially increase bruising. Avoid blood thinners unless medically necessary or as directed by your physician, as these can also increase bruising. Refrain from smoking, which may impair healing. One study suggests smoking can reduce skin blood flow by up to 40%, potentially delaying recovery.
- Consult: Check with your healthcare provider for personalized product recommendations.
- Prepare: Ensure skin is clean and sterilized before and after the procedure to minimize the risk of infection.
- Caution: Avoid applying to areas with prior dermal fillers as there could be unpredictable results.
- Maintain: Consistency with aftercare contributes to achieving the best possible results.
DIRECTIONS:
- Aftercare instructions have been divided into clear, manageable sections for effective implementation:
- Skincare: Begin with gentle cleansing and proceed with moisturizing and sun protection, avoiding harsh products.
- Activity: Focus on keeping cool and limiting physical exertion and exposure to heat post-procedure.
- General Care: Protect skin from sun, follow healthcare provider’s advice strictly, and avoid certain behaviors like touching or smoking that could impair healing.
- Preparation and Caution: Ensure proper preparation and consider all cautionary measures to prevent complications.
- Consultation: Always consult healthcare provider for tailored advice and product suggestions.
This structured approach facilitates adherence to the aftercare routine, supporting optimal recovery post-Korean salmon DNA injection.
Anticipated Outcomes
Korean salmon DNA injections improve skin in several ways by boosting collagen and hyaluronic acid production. This results in firmer, more hydrated skin. The treatment eases inflammation and helps skin repair itself, leading to smoother skin with a more even color and lessening wrinkles.
Cellular regeneration revitalizes fibroblast activity, making skin more elastic. As a result, the skin rejuvenates quickly, leading to tighter, fresher-looking skin. You can expect to see less sagging skin and a brighter appearance. Specifically, the improvements include:
- Better skin texture.
- Fewer fine lines.
- Increased skin hydration.
- Improved skin elasticity.
Compared to other fillers, salmon DNA injections offer gradual, natural improvements by focusing on skin health. Pricing varies from place to place; therefore, comparing costs with the benefits and other options is advisable to determine what works best for you.
Longevity and Upkeep
Visible improvements generally appear within a few weeks of starting treatment, with results lasting for several months. Individual results vary based on skin condition and treatment frequency. Expect effects to endure for months after the initial 3-4 sessions. Schedule follow-up appointments every 6-12 months to maintain these results. Consulting a professional is essential to tailor the treatment schedule to your unique situation.
To prolong the benefits, it is crucial to maintain consistent skincare practices. Moisturize regularly and protect your skin from the sun. Avoid the use of blood thinners, alcohol consumption, and smoking to facilitate healing and preserve results. Shield the treated area from sun exposure and apply sunscreen diligently. Opt for lightweight, non-comedogenic skincare products.
For the first 48 hours post-treatment, avoid intense exercise, exposure to heat, and activities that induce sweating. Manage any discomfort, redness, or swelling with gentle cleansing, moisturizing, and the application of cold compresses. Proper hydration and a consistent skincare routine significantly improve treatment outcomes.
Adherence to aftercare instructions and lifestyle modifications can enhance the longevity of treatment results.
Global Regulatory Status

Korean Salmon DNA injections, notably Rejuran Healer, present an intriguing case in the global landscape of cosmetic treatments due to their varying regulatory statuses across different regions.
Regulatory Approval Overview:
- Korea and Select Countries Approval: Rejuran Healer has been approved by the Korean FDA, indicating a level of acceptance within the region. Certain Asian and European countries have also authorized its use, suggesting a broader international validation despite differing standards.
- U.S. FDA Review Progress: Conversely, the U.S. FDA is still in the process of reviewing Rejuran Healer, signaling a divergence in regulatory acceptance compared to international norms.
- International Safety Compliance: Regardless of region, Rejuran Healer meets recognized international safety standards, ensuring a baseline of quality and safety across its approved jurisdictions.
Administration Requirements:
- Professional Administration: The treatment must be administered by licensed professionals, emphasizing the need for qualified expertise in its application.
Clinical Evidence and Efficacy:
Research, including studies such as the one conducted by Khan et al. in 2022, provides clinical evidence supporting the efficacy of Korean Salmon DNA injections. These studies highlight regenerative properties that contribute to improved skin quality, underscoring the treatment’s potential benefits. Ongoing monitoring and clinical trials continue to refine understanding of its mechanisms and long-term effects, ensuring patient safety and treatment efficacy.
Due to its complex nature and varying regulatory environments, it’s crucial for individuals considering Korean Salmon DNA injections to consult with qualified healthcare professionals to navigate the available options and understand the treatment’s implications within their specific regional context.