Taking or applying drugs to our bodies sometimes comes with unwanted side effects. This is because the human body works in a complex way, in that taking or applying a drug won’t target just one thing but would also risk affecting other aspects of the body’s processing. One of these side effects is hair loss when one applies ciclopirox olamine cream.
So can PRP injections help solve hair loss from ciclopirox olamine cream? Yes, PRP injections can help solve hair loss from ciclopirox olamine cream. PRP is an effective hair loss treatment that works through growth factors that encourage the production of new blood vessels, prolongation of the anagen phase of the hair growth cycle, and regulation of anti-apoptotic mediators.
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SHOPSeborrheic dermatitis is an inflammatory skin disease affecting the scalp, face, and body folds, which are the areas of the body rich in sebaceous glands (the glands that produce sebum or oil). The exact cause of this skin condition is still unknown, although several possible etiologies are pointed out, such as the following:
This skin disorder is also associated with hair loss because of the itchiness that results from the inflammation and irritation due to the pronounced production of sebum. This itchiness causes the person suffering from the disorder to relentlessly scratch their scalp, damaging hair follicles which then leads to impairments in natural hair growth, ultimately leading to hair loss.
Seborrheic dermatitis is usually treated using ciclopirox olamine cream, an agent with antifungal, antibacterial, and anti-inflammatory properties, which works by chelation of Fe3+ that has an inhibitory effect on microbial enzymes, along with inhibition of metal-dependent enzymes.
Studies have shown the efficacy and safety of ciclopirox olamine cream in patients with seborrheic dermatitis. Shampoo forms of this antifungal also are shown to reduce the remission of seborrheic dermatitis.
However, ciclopirox olamine cream isn’t without side effects. One of the side effects of this antifungal is hair loss, which is ironic considering this agent addresses seborrheic dermatitis and should then promote the prevention of hair loss caused by seborrheic dermatitis.
Hair growth was supposedly the effect of the application of antifungals to the scalp because treatment of Malassezia, the causative agent of scalp disorders like seborrheic dermatitis, psoriasis, and atopic dermatitis, means controlling the oxidative stress caused by the said fungal species.
Although not consistent with that in ciclopirox olamine cream, other antifungals have demonstrated this effect, such as ketoconazole and zinc pyrithione-based shampoo.
Studies have shown that the use of 2% ketoconazole shampoo, aside from being an effective treatment against seborrheic dermatitis, may also be used against androgenetic alopecia. This is because ketoconazole has hair growth stimulating properties, although the exact mechanism behind this is yet to be elucidated.
A zinc pyrithione-based shampoo was demonstrated to have comparable effects on hair growth when compared to 5% topical minoxidil. This is because of the decreased oxidative stress associated with the use of zinc pyrithione-based shampoo.
Specifically formulated for the scalp, PEP Scalp is a groundbreaking alternative to PRP treatment for hair and scalp rejuvenation. It helps patients achieve similar results without the need to invest in a centrifuge.
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SHOPHair loss may also be caused by other drugs, not just ciclopirox olamine cream. This is a condition called drug-induced alopecia, a kind of hair loss that occurs 3 months after the use of certain drugs.
Some of the drugs that cause drug-induced alopecia are as follows:
Some drugs affect the hair growth cycle at the telogen phase and cause hair loss due to disruptions in this phase. These drugs include the following:
In contrast to this, some drugs affect the hair growth cycle at the anagen phase and cause hair loss due to disruptions in this phase. These drugs include the following:
Drug-induced alopecia usually goes away on its own upon stopping the medication that causes it. However, in cases where hair loss persists even after stopping the medication, hair loss treatments such as platelet-rich plasma injections should be considered.
Platelet-rich plasma injections can help solve hair loss from ciclopirox olamine cream and other types of hair loss through mechanisms that are yet to be elucidated. However, some proposed mechanisms include the following:
Platelet-rich plasma injections are an autologous preparation, meaning the formulation is derived from the patient’s own blood components. Standardization of the process is still being discovered, although all platelet-rich plasma preparation comes in a 3-step procedure. These 3 steps may be simplified as follows:
There are also competing views regarding the need for activation of platelet-rich plasma before use. In protocols that do activate, calcium gluconate is one of the most commonly employed activators. Commercial kits for platelet-rich plasma preparation are also available.
Since platelet-rich plasma injections are derived from the patient’s own blood, it’s then guaranteed to be safe and free from reactions associated with the administration of foreign bodies like allergic reactions and being risk factors for the transmission of communicable diseases.
Side effects associated with platelet-rich plasma injections are usually caused by the method of preparation and administration and not by the formulation itself. These side effects include the following:
Platelet-rich plasma injections are also made as comfortable as possible by medical professionals who administer them to patients with hair loss. Common techniques employed to minimize discomfort associated with the procedure include the following:
With these safety considerations, it’s also important to keep in mind that platelet-rich plasma injections aren’t for everyone. People who can’t undergo this procedure include those with other medical conditions such as the following:
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SHOPPlatelet-rich plasma injections are a safe and effective procedure with minimal downtime owing to their minimally-invasive administration. Patients who underwent this procedure may immediately return to their normal activities after the procedure, although pre- and post-care tips must still be followed to facilitate a faster recovery process after PRP injections.
Prior to the treatment, it’s best to prepare oneself and the area where the formulation will be administered to prevent the aggravation of side effects. Pre-care tips include the following:
It’s also best to follow safety precautions after PRP injections despite their minimal downtime. Post-care tips include the following:
To further improve the hair growth benefits of platelet-rich plasma treatments, it’s advisable to combine this procedure with other formulations and procedures that can also promote the improvement of the appearance of thinning hair. One of these formulations that are good for the hair is the PEP Factor.
PEP Factor is an innovative and high-quality hair care product made of natural ingredients such as nourishing peptides. It’s also topically applied, thus ensuring its safety and minimizing the occurrence of side effects associated with injections or other ways of administration.
The active ingredients of the PEP Factor are the basic fibroblast growth factor (bFGF) and copper peptide. Basic fibroblast growth factor works in the same way as the growth factors found in platelet-rich plasma, in that it’s also capable of promoting the growth and proliferation of hair cells.
Similarly, the copper peptide has antioxidant properties, thus preventing the exacerbation of hair loss brought by oxidative stress.
Platelet-rich plasma injections are an effective procedure that promotes hair growth for drug-induced hair loss like that from ciclopirox olamine cream. It also works for other types of hair loss like androgenetic hair loss.
At FACE Med Store, we offer high-quality hair care products and medical supplies, especially for any hair health concern like hair growth or hair restoration. Our staff will gladly help our clients find what’s suitable for their specific beauty or medical concerns. Contact us today at info@facemedstore.com to learn more about the products that we offer.